Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on mutation processes that contribute to cancer and inherited genetic conditions ...

The study, by Dr Greg Ngo and Professor Duncan Baird from Cardiff University’s School of Medicine, reveals the mechanism behind chromoanasynthesis, a catastrophic type of chromosome rearrangement that ...

Researchers at the University of California San Diego (UCSD) have demonstrated an intriguing new variation on the CRISPR gene-editing system, which involves fixing a mutation on one chromosome by ...

A chromosome consists of a molecule of DNA and proteins. During these mutations, a long segment of DNA may be inserted into a chromosome, deleted from a chromosome, flipped around within a chromosome, ...

Rett syndrome is a rare developmental disorder, most often due to a mutation in the MECP2 gene on the X chromosome, but it’s not usually inherited. Advances in genetics have launched a new era in ...

An international study has identified more than 50 genes on the X chromosome in which mutations may cause poor sperm production. Nearly half of all men with low or zero sperm count have no medical ...