Reintroduction of the Cyclin A2 gene enables adult human cardiomyocytes to divide, producing functional daughter cells and promoting heart repair. The therapy uses a replication-deficient adenoviral ...

A study led by Maria Carmo-Fonseca at GIMM has helped clarify one of the main limitations of lab-grown heart cells, which are widely used around the world to study heart disease and test new drugs.

The framework of CASHeart. (A) Overview of the data collection and data processing workflow in the CASHeart Database. (B) Introduction to the main interfaces of the CASHeart website. The human heart ...

From left to right - the cell in the initial frame is from a 55-year-old donor heart. The next image shows the cell rounding up after receiving Cyclin A2 and the cell division takes place shortly ...

Around the globe, heart disease remains one of the top causes of death. Once patients begin to suffer from serious heart problems, like heart attacks and heart failure, the heart muscles become ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...

A crucial new mechanism that helps explain how the heart’s major blood vessels form during early development – and how disruptions to this process can lead to serious congenital heart defects – has ...