Nature

Copy Number Variation in Animal Genomes

Copy number variations (CNVs) are a pervasive form of genomic variation that entail duplications or deletions of DNA segments ranging from kilobases to megabases. In animal genomes, CNVs contribute ...
Nature

Amylase Gene Copy Number Variation and Its Impact on Obesity and Diabetes

The amylase gene family, particularly AMY1, exhibits extensive copy number variation (CNV) that modulates salivary amylase production and, consequently, the efficiency of dietary starch digestion.
Medscape

Genes Disrupted by Copy Number Variations in Autism Spectrum Disorders

June 14, 2010 — Individuals diagnosed with autism spectrum disorders (ASDs) have nearly 20% more gene copy number variations (CNVs) overall and more than 60% more CNVs in genes associated with ...
ascopubs.org

Detection of Copy-Number Variation in Circulating Cell-Free DNA in Patients With Uveal Melanoma

Association of Timely Comprehensive Genomic Profiling With Precision Oncology Treatment Use and Patient Outcomes in Advanced Non–Small-Cell Lung Cancer Somatic chromosomal alterations, particularly ...
ascopubs.org

Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data

SNF-CLIMEDIN: A Randomized Trial of Digital Support and Intervention in Patients With Advanced Non–Small Cell Lung Cancer. A Hellenic Cooperative Oncology Group Study Shallow whole-genome sequencing ...